

Conventional mandibular fixation relies on rigid titanium plates that are significantly stiffer than bone. This mismatch disrupts natural load transfer.
Despite advances in geometry and customization, surgeons still lack tools to evaluate how fixation will perform in a specific patient.
RegenFix is developing a biomechanics-driven fixation platform that combines:
Addressing the fundamental mismatch between implant stiffness and bone — a key driver of stress shielding and long-term device failure. RegenFix pairs stiffness-matched Nitinol implants with patient-specific biomechanical simulation to restore physiologic loading, improve healing outcomes, and reduce revision risk.

Large‑animal preclinical validation completed. Alignment between predicted and observed biomechanical performance.
Engineered porosity for stiffness-matched, PBF-LB, Nickel-Titanium mandibular graft fixation plates
https://www.sciencedirect.com/science/article/pii/S0264127525017861
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